We want to learn how cells die in order to understand how to live.

Selected Publications

  • Taraborrelli, L*., Peltzer, N*., Montinaro, A., Kupka, S., Rieser, E., Hartwig, T., Sarr, A., Darding, D., Draber, P., Haas, T.L., Akarca, A., Marafioti, T., Pasparakis, M., Bertin, J., Gough, P.J., Bouillet, P., Strasser, A., Leverkus, M., Silke, S., Walczak, H. LUBAC prevents lethal dermatitis by combined inhibition of TNF-, TRAIL- and CD95L-mediated cell death. Nature Communications 9:3910, 2018 .*co-first authors
  • Peltzer, N*., Darding, M*., Montinaro, A., Draber, P., Draberova, H., Kupka, S., Rieser, E., Fisher, A., Hutchinson, C., Taraborrelli, L., Hartwig, t., Lafont, E., Haas, T.L., Shimizu, Y., Böiers, C., Sarr, A., Rickard, J., Alvarez-Diaz, S., Ashworth, M.T., Beal, A., Enver, T., Bertin, J., Kaiser, W., Strasser, A., Silke, J., Bouillet, P., Walczak, H. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature 557: 112–117, 2018.*co-first authors
  • Peltzer, N*., Rieser, E.*, Taraborrelli, L., Draber, P., Darding, M., Pernaute, B., Shimizu, Y., Daboh, A., Draberova, H., Montinaro, A., Martinez-Barbera, J.P., Silke, J., Rodriguez, T.A. and Walczak, H. HOIP deficiency caused embryonic lethality by aberrant TNFR1- mediated endothelial cell death. Cell Reports 9: 153-165, 2014 .*co-first authors
  • Peltzer, N., Vanli G., Yang, JY., Widmann, C. Role of mTOR, Bad and Survivin in    RasGAP fragment N-mediated cell protection. Plos One 27;8(6):e68123. 2013
  • Khalil, H.*, Peltzer, N*., Walicki, J., Yang, JY., Dubuis, G., Gardiol, N., Held, W., Bigliardi,     P., Marsland, B., Liaudet, L. and Widmann, C. Caspase-3 protects stressed organs against cell death. Molecular and Cellular Biology 32(22):4523-33, 2012 .*co-first authors
  • Peltzer, N., Bigliardi, P., Widmann, C. UV-B induces cytoplasmic survivin expression in mouse epidermis. Journal of Dermatological Science 67(3):196-9, 2012.
  • Peltzer, N., Roques, N., Poinsot, V., Aguilar, OM., Batut, J., Capela, D. Auxotrophy accounts for nodulation defect of most Sinorhizobium meliloti mutants in the branched- chain amino acid biosynthesis pathway. Molecular Plant-Microbe 21(9):1232-41, 2008.